Propecia Hair loss Treatment
Propecia Hair loss Treatment
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Propecia
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How PROPECIA® (finasteride) Works
PROPECIA specifically inhibits the enzyme type II 5 alpha-reductase to decrease serum and scalp DHT. (The relative contributions of these reductions to the treatment effect of PROPECIA have not been defined.)
PROPECIA lowers DHT. Lowering DHT appears to:
Inhibit the further miniaturization of affected hair follicles.
Help restore miniaturized hair follicles to regrow visible hair
In a clinical study, PROPECIA did not appear to affect hair growth on other parts of the body.
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Important Information About PROPECIA
PROPECIA is the first and only FDA-approved oral treatment for male pattern hair loss in MEN ONLY.
Safety and efficacy were established in men, aged 18 to 41, with mild to moderate hair loss of the vertex and anterior mid-scalp area. Efficacy in bitemporal recession has not been established. PROPECIA is not indicated in women or children.
No dosage adjustments needed, regardless of age or renal function. Caution should be used in patients with liver function abnormalities, as finasteride is metabolized extensively in the liver.
No drug interactions of clinical importance have been identified.
Compounds that have been tested in men include antipyrine, digoxin, propranolol, theophylline, and warfarin, and no interactions were found.
In men older than 41 undergoing a PSA test while taking PROPECIA, consideration should be given to doubling the PSA level. In men younger than 40, PSA is not routinely measured.
In clinical studies with PROPECIA in men 18 to 41 years of age, the mean value of serum prostate-specific antigen (PSA) decreased from 0.7 ng/mL at baseline to 0.5 ng/mL at Month 12. When finasteride is used in older men who have benign prostatic hyperplasia (BPH), PSA levels are decreased by approximately 50%.
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