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Sulfasalazine
for
alopecia
areata.
Ellis CN,
Brown
MF,
Voorhees
JJ.
Department
of
Dermatology,
1910 A.
Alfred
Taubman
Center,
University
of
Michigan
Medical
School,
Ann
Arbor,
MI
48109-0314,
USA.
J Am
Acad
Dermatol
2002
Apr;46(4):541-4
Sulfasalazine
is used
as a
therapy
for
various
autoimmune
conditions,
including
psoriasis;
its
effectiveness
is
presumed
to be
the
result
of its
immunomodulatory
effects.
We have
treated
patients
with
severe
alopecia areata
with
sulfasalazine
as part
of our
dermatology
practice
and have
noticed
cosmetically
acceptable
regrowth
in 23%
of
patients
in whom
a
response
could be
determined.
I
n view
of its
good
safety
profile, sulfasalazine
may be
considered
for
systemic
treatment
of
severe
alopecia
areata.
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