Avodart V's Propecia

Avodart/Dutasteride is very similar to Finasteride, the active ingredient in Propecia. They both help reduce the amount of the male hormone, DHT, in the scalp area. However, Avodart/Dutasteride inhibits the activities of two types of 5-alpha-reductase enzymes. In contrast, Propecia (Finasteride) only inhibits one type. This makes Avodart/Dutasteride a supposedly  more powerful and faster-acting weapon against hair loss than Finasteride.

Avodart V's Propecia: DHT hormone suppression

Effectiveness of Acodart/Dutasteride has been evaluated at different daily dosages, ranging from 0.5mg to 2.5mg and 5.0mg per day.

At a daily dosage of 2.5mg or 5.0mg, Avodart/Dutasteride suppresses close to 100% of DHT. This compares favourably with 5.0mg daily dosage of Propecia (Finasteride) which suppresses only 70% of DHT.

However Avodart/Dutasteride is very effective at small doses. At a daily dose of 0.5mg, DHT inhibition is close to 90%. Also, the level of DHT suppression is not significantly greater between 2.5mg and 5.0 mg.

Avodart V's Propecia: increasing hair count

Phase II trials of Avodart/Dutasteride showed that after six month of treatment, the hair counts measured in a 1 inch diameter circle increased by an average 96 hairs with 0.5mg Avodart/Dutasteride, compared to an average 72 hairs with 5mg Propecia (Finasteride).

So these initial trials show that Avodart/Dutasteride is around 30% more effective than Propecia in promoting hair regrowth.
 

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